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NateraEngineering Lab Informatics

Principal Software Engineer

Austinonsiteprincipal$25K$31K

via Greenhouse

About this role

Position Summary We are seeking an accomplished Principal Software Engineer to shape the future of lab software platforms powering high-throughput, regulated laboratory operations. In this role, you will define technical direction across complex, distributed systems and lead the evolution of software applications that drive lab automation, efficiency, and operational excellence. You will operate as a hands-on technical leader with deep ownership, from architecture and design through critical implementation to influencing lab operations processes, engineering standards, and long-term platform strategy. This role is ideal for a systems thinker who thrives in ambiguity, makes sound tradeoffs, and raises the technical bar for the entire organization. Responsibilities…

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What we'd score you on

reqspace match rubric

Five dimensions, recruiter-grade. Upload your resume and we'll generate a written explanation of where you fit and where the gaps are.

1

Skills match

For this role: typescript, python, java, sql, react…

2

Level fit

This role is principal-level. We check your trajectory against it.

3

Domain experience

Your work in the role's domain matters more than your years total. We weight recent and direct experience.

4

Recency

A skill you used last quarter weighs more than one from five years ago. We grade on recency, not lifetime.

5

Location fit

This role is based in Austin. We weight your proximity and willingness to relocate.

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Skills in this role

Pulled from the job description. These are the keywords we'll weight when scoring your fit.

typescriptpythonjavasqlreactmysqldynamodbrdsawss3lambda

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