Member of Technical Staff, Physical AI

The opportunity Substrate is building a laboratory that runs itself. Robotics move the samples and the instruments take the measurements, but a lab that operates without people standing over it has to perceive what it is doing: every camera frame, every sensor stream, every instrument log, captured and understood in real time. That perception layer does not exist yet. You would build it. This is the work that lets an autonomous lab catch its own mistakes, a misfired liquid handler or a transfer that did not complete, the moment they happen, and that captures the full provenance of every experiment as it runs. Provenance is one half of the bar, with scientific quality, that makes Substrate's data worth training on, and it only exists if it is captured at the source.…